The  MagSure Micro RNA Isolation Kit is specially developed to isolate high-quality small RNA fractions including microRNAs. The total RNA are isolated by solid-phase reversible immobilization (SPRI) on silica columns. This kit uses the RnaBio RNA Isolation Reagent for the quick lysis of cells, followed by binding of long RNA to silica column and purification of small RNAs including microRNAs using magnetic silica beads. In sum, this kit can be used to isolate high-quality total RNA from a variety of samples, including animal cells, tissues, plants, and yeast.